Lenalidomide for the Treatment of Resistant Discoid Lupus Erythematosus

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Lenalidomide for the treatment of resistant discoid lupus erythematosus.

BACKGROUND Discoid lupus erythematosus (DLE) is a chronic, disfiguring disease that is characterized by scaly, erythematous, disk-shaped patches and plaques followed by atrophy, scarring, and dyspigmentation. It is refractory to standard therapies in a small population of patients. We investigated the use of lenalidomide, a thalidomide analogue, as a novel alternative therapy in 2 cases of refr...

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Medical and surgical treatment for discoid lupus erythematosus.

A case is presented of a 27-year-old Caucasian woman that presented with an oval purplish patch with defined borders on her right cheek. It was swollen and tense, with a mottled surface due to scarring. Histologic examination indicated discoid lupus erythematosus and the patient was initially treated with medical therapy. The lesion relapse and cosmetic results convinced us to propose surgical ...

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Discoid lupus erythematosus: a profile.

OBJECTIVE To determine the demographic data, clinical pattern and therapeutic outcome in patients with discoid lupus erythematosus (DLE). STUDY DESIGN Case series. PLACE AND DURATION OF STUDY The Department of Dermatology, Liaquat University of Medical and Health Sciences, Jamshoro, from January 2004 to December 2008. METHODOLOGY Patients of either gender aged above 18 years diagnosed wit...

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ژورنال

عنوان ژورنال: Archives of Dermatology

سال: 2009

ISSN: 0003-987X

DOI: 10.1001/archdermatol.2009.30